Each of my test lab servers took between 20 and 30 minutes to upgrade, but your performance will no doubt vary.Paul is a Microsoft MVP for Office Servers and Services.For example if you have two Hub Transport servers in a site, upgrade them one at a time.The upgrades steps are very straightforward and easy to follow. When the splash dialog appears click Install Microsoft Exchange Server upgrade. Warnings will not prevent you from proceeding, but you should pay attention to them anyway as they are often important.For an example of how to do this with Windows NLB see the following article: For other load balancers refer to your vendor documentation for how to take servers out of the load balanced array for maintenance and updates.
For Hub Transport, Edge Transport, and Unified Messaging servers there are no special steps required other than to manage your upgrades in a way that aligns with whatever high availability you have in place or those server roles.
Microsoft has released Service Pack 3 for Exchange Server 2010.
This is a significant release that delivers some key functionality to customers such as support for Windows Server 2012, support for co-existence with Exchange Server 2013 CU1, and general bug fixes and security updates.
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Client Access servers are the first server role to update, and you should begin with the internet-facing site if you have multiple sites in your organization.